Family studies and aetiology of club foot.
نویسنده
چکیده
Congenital club foot and talipes are used to describe various abnormalities of the foot in the newborn child. The most serious of these is talipes equinovarus in which there is plantar flexion of the ankle and inversion of the foot. This deformity is difficult to treat, having a marked tendency to recur, and causes a real disability. About half the cases are bilaterally affected. Patients frequently attend hospital for the first Io-i5 years of life. A long-term follow up of the results of treatment of patients with talipes equinovarus has been reported elsewhere (WynneDavies, I964a). The family findings in a series of patients with talipes equinovarus, mild (postural) talipes equinovarus, talipes calcaneo-valgus, and metatarsus varus have been reported in summary form (Wynne-Davies, I964b). In this paper the family data, especially that on talipes equinovarus, are presented and discussed in more detail. Cases secondary to spina bifida, cerebral palsy, and arthrogryposis are not included.
منابع مشابه
Genetics of club foot in Maori and Pacific people.
The role of major gene and multifactorial inheritance in the aetiology of club foot in the New Zealand Polynesian population was studied using 287 New Zealand Maori and Pacific club foot families. The club foot family data were analysed by complex segregation analysis under the mixed model using the computer program POINTER. This analysis shows that the best genetic model for club foot in this ...
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Idiopathic talipes equinovarus (ITEV) or isolated club foot deformity is a common birth defect having an average birth prevalence of 1 per 1000 live births. 2 However, the birth prevalence of ITEV varies among different populations, ranging from 0.39-7 per 1000 live births, with the highest rate in the Hawaiian and Maori populations. ITEV occurs more frequently in males and the skewed 2:1 ratio...
متن کاملThe causes of congenital club foot.
Hippocrates was the first to suggest that permanent crippling can follow abnormal intrauterine pressure. More recently, Browne (1936) has been the foremost exponent of the view that this is a major cause of congenital club feet. The theory had first been challenged in the early 19th century by the authors of several very detailed studies on the condition. Little (1839) felt that the variety of ...
متن کاملFamily Studies and the Cause of Congenital Club Foot. Talipes Equinovarus, Talipes Calcaneo-valgus and Metatarsus Varus.
This paper on congenital club foot in Devonshire is based on a study of 635 patients treated at the Princess Elizabeth Orthopaedic Hospital, Exeter. It deals with the family history and associated congenital abnormalities, and attempts to clarify the causation of club foot. Particular attention is given to talipes equinovarus, and there are short notes on talipes calcaneo-valgus and metatarsus ...
متن کاملClub foot, an adverse outcome of early amniocentesis: disruption or deformation? CEMAT. Canadian Early and Mid-Trimester Amniocentesis Trial.
An association between the occurrence of club foot and early amniocentesis has been reported. The largest of these randomised studies was the Canadian Early and Mid-Trimester Amniocentesis Trial. Data describing the neonatal outcome, focusing on this association, are presented. Possible mechanisms for the association and the implications for the development of club foot are discussed.
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 2 4 شماره
صفحات -
تاریخ انتشار 1965